The Bosnia & Herzegovina international was an 83rd minute substitute at the Mapei Stadium, as the Giallorossi ultimately drew 2-2 with Sassuolo.
It was Dzeko's 193rd game in Serie A for the club - he has played a further 27 in the Champion League, 22 in the Europa League and eight in the Coppa Italia.
Dzeko has scored 116 goals for the club to date - putting him third on the club's list of all-time leading goalscorers.
Congratulations, Edin!
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