Afena-Gyan, 19, joins the Serie A side on a permanent deal.
The young striker joined the Giallorossi's youth system at the start of 2021, making his professional debut for the club later that same year.
In total he made 22 appearances in Giallorossi, scoring two goals - both of them coming against Genoa in a memorable substitute appearance in October 2021.
He was also a part of the matchday squad as Roma lifted the Europa Conference League in May this year.
The club would like to wish Felix the best of luck for the future.
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