The Serbian full-back has been omitted from the squad list for the game to rest and recuperate, having been almost ever-present for the Giallorossi so far this season.
His place in the squad list is taken by young full-back Nura Abdullahi.
Wednesday's game gets underway at 17:30 CET.
See the full list of available players below.
Alisson Becker
Lukasz Skorupski
Andrea Romagnoli
Juan Jesus
Hector Moreno
Federico Fazio
Nura Abdullahi
Bruno Peres
Emerson Palmieri
Kostas Manolas
Leandro Castan
Radja Nainggolan
Kevin Strootman
Lorenzo Pellegrini
Daniele De Rossi
Maxime Gonalons
Alessandro Florenzi
Gerson
Diego Perotti
Edin Dzeko
Patrik Schick
Cengiz Under
Stephan El Shaarawy
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